Scientific Papers (published)
Otto W. Witte
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Redecker
C, Luhmann HJ, Hagemann G, Fritschy JM, Witte OW.
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here
Differential downregulation of GABAA receptor subunits in widespread
brain regions in the freeze-lesion model of focal cortical malformations.
J Neurosci. 2000 Jul 1;20(13):5045-53.
Witte
OW, Bidmon HJ, Schiene K, Redecker C, Hagemann G.
Functional differentiation of multiple perilesional zones after focal
cerebral ischemia.
J Cereb Blood Flow Metab. 2000 Aug;20(8):1149-65. Review.
Gladilin
S, Bidmon HJ, Divanach A, Arteel GE, Witte OW, Zilles K, Sies H.
Ebselen lowers plasma interleukin-6 levels and glial heme oxygenase-1
expression after focal photothrombotic brain ischemia.
Arch Biochem Biophys. 2000 Aug 15;380(2):237-42.
Witte
OW.
Physiological basis of pathophysiological brain rhythms.
Acta Neurobiol Exp (Warsz). 2000;60(2):289-97. Review.
Kowalik
ZJ, Witte OW.
Deterministic brain oscillations in the magnetoencephalogram.
Acta Neurobiol Exp (Warsz). 2000;60(2):195-202.
Hagemann
G, Redecker C, Witte OW.
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Intact functional inhibition in the surround of experimentally induced
focal cortical dysplasias in rats.
J Neurophysiol. 2000 Jul;84(1):600-3.
Redecker
C, Hagemann G, Gressens P, Evrard P, Witte OW
Reprint
Cortical dysgenesis: recent aspects regarding pathogenesis and pathophysiology
Nervenarzt 2000 Apr;71(4):238-48
Seitz, R.J., Volkmann, J., Witte, O.W.
Functional Mapping of the Human Brain.
The Neuroscientist 6, 2000, 75 - 76
Keyvani
K, Reinecke S, Abts HF, Paulus W, Witte OW.
Reprint
Suppression of proteasome C2 contralateral to ischemic lesions in rat
brain.
Brain Res. 2000 Mar 10;858(2):386-392.
Kowalik
Z.J., Steriade M., Skinner J.E., Witte, O.W.
Detecting oscillations in cortical and subcortical structures.
Acta Neurobiol. Exp. 60, 2000, 45 - 48
Feldkamp,
J., Becker, A., Witte, O.W., Scharff, D, Scherbaum, W.A.
Long-term anticonvulsant therapy leads to low bone mineral density
- evidence for direct drug effects of phenytoin and carbamazepine on human
osteoblast-like cells.
Exp. Clin. Endocrinol. Diabetes 108 2000 37-43
G. Hagemann, O.W.Witte, B. Gottstein
Isolated Echinococcus granulosus hydatid cyst in the CNS with severe
reaction to treatment - Reply
Neurology 54: (3) 779-779 FEB 8 2000
Wunderlich
G, Schuller MF, Ebner A, Holthausen H, Tuxhorn I, Witte OW, Seitz
RJ.
Reprint
Temporal lobe epilepsy with sensory aura: interictal glucose hypometabolism.
Epilepsy Res. 2000 Feb;38(2-3):139-49.
Holthoff
K, Witte OW. Reprint
Directed spatial potassium redistribution in rat neocortex.
Glia. 2000 Feb 1;29(3):288-92.
Witte
OW, Freund HJ.
Neuronal dysfunction, epilepsy, and postlesional brain plasticity.
Adv Neurol. 1999;81:25-36. Review.
Witte
OW, Bruehl C.
Distant functional and metabolic disturbances in focal epilepsy.
Adv Neurol. 1999;81:383-8. Review.
Neumann-Haefelin
T, Witte OW.
Periinfarct and remote excitability changes after transient middle
cerebral artery occlusion.
J Cereb Blood Flow Metab. 2000 Jan;20(1):45-52.
H.
Jokeit, A. Ebner, S. Arnold, M. Schüller, C. Antke, Y. Huang,
H. Steinmetz, R.J. Seitz, O.W. Witte.
Reprint
Bilateral depressions of hippocampal volume, glucose metabolism, and
Wada hemispheric memory performance are related to the duration of mesial
temporal lobe epilepsy.
J. Neurol., 1999, 246, 926 - 933
Oue
M, Witte OW, Neumann-Haefelin T, Schiene K, Schroeter M, Zilles
K
Changes in GABA(A) and GABA(B) receptor binding following cortical
photothrombosis: a quantitative receptor autoradiographic study.
Neuroscience 1999, 93, 1233-1240
Que
M, Schiene K, Witte OW, Zilles K
Widespread up-regulation of N-methyl-D-aspartate receptors after focal
photothrombotic lesion in rat brain.
Neurosci. Lett. 1999, 273, 77-80
Schroeter
M, Jander S, Witte OW, Stoll G
Heterogeneity of the microglial response in photochemically induced
focal ischemia of
the rat cerebral cortex.
Neuroscience 1999 Apr;89(4):1367-77
Loose
R, Schnitzler A, Sarkar S, Schmitz F, Volkmann J, Frieling T, Freund HJ,
Witte
OW, Enck P
Cortical activation caused by mechanical oesophageal activation: a
neuromagnetic study.
Neurogastroenterol Motil 1999 Jun;11(3):163-171
Azari
NP, Knorr U, Arnold S, Antke C, Ebner A, Niemann H, Pettigrew KD, Witte
OW, Seitz RJ
Reorganized cerebral metabolic interactions in temporal lobe epilepsy.
Neuropsychologia 1999 Jun;37(6):625-36
G.
Hagemann, B. Gottstein, O.W. Witte
Isolated Echhinococcus granulosus hydatid cyst in the central nervous
system with severe reaction to treatment.
Neurology 1999 Mar 23;52(5):1100-1
S.
Reinecke, M. Lutzenburg, G. Hagemann, C. Bruehl, T. Neumann-H?felin,
and O.W. Witte
Electrophysiological Transcortical Diaschisis After Middle Cerebral
Artery Occlusion (MCAO) in Rats.
Neurosci Lett 1999 Feb 12;261(1-2):85-8
Schiene
K, Staiger JF, Bruehl C, Witte OW
Enlargement of cortical vibrissa representation in the surround of
an ischemic cortical lesion.
J Neurol Sci 1999 Jan 1;162(1):6-13
Schnitzler
A, Volkmann J, Enck P, Frieling T, Witte OW, Freund HJ
Different cortical organization of visceral and somatic sensation in
humans.
Eur J Neurosci 1999 Jan;11(1):305-15
Hagemann
G, Hoeller M, Bruehl C, Lutzenburg M, Witte OW
Effects of tetanus toxin on functional inhibition after injection in
separate cortical areas in rat
Brain Res 1999 Feb 6;818(1):127-134
Tobias
Neumann-Haefelin, Frank Bosse, Christoph Redecker, Hans-Werner M?ller,
Otto
W. Witte:
Upregulation of GABAA-receptor alpha1- and alpha2-subunit mRNAs following
ischemic cortical lesions in rats.
Brain Res 1999 Jan 16;816(1):234-237
K.Holthoff,
O.W.
Witte
Intrinsic optical signals in vitro: A new tool to measure alterations
in extracellular space with 2-dimensional resolution.
Brain Res Bull 1998 Dec;47(6):649-55
Bruehl
C, Hagemann G, Witte OW
Uncoupling of blood flow and metabolism in focal epilepsy.
Epilepsia 1998 Dec;39(12):1235-42
O.W.
Witte
Lesion-induced plasticity as a potential mechanism for recovery and
rehabilitative training.
Current Opinions in Neurology 11, 1998, 655 - 662
Bruehl
C, Wagner U, Huston JP, Witte OW
Thalamo-cortical circuits causing remote hypometabolism during focal
interictal epilepsy.
Epilepsy Res 1998 Nov;32(3):379-87
Qu
M, Buchkremer-Ratzmann I, Schiene K, Schroeter M, Witte OW, Zilles K:
Bihemispheric reduction of GABAA receptor binding following focal cortical
ischemia in the rat brain.
Brain Res 1998 Dec 7;813(2):374-80
Redecker
C, Lutzenburg M, Gressens P, Evrard P, Witte OW, Hagemann G
Excitability changes and glucose metabolism in experimentally induced
focal cortical dysplasias.
Cereb Cortex 1998 Oct-Nov;8(7):623-34
Neumann-Haefelin
T, Staiger JF, Redecker C, Zilles K, Fritschy JM, Mohler H, Witte OW
Immunohistochemical evidence for dysregulation of the GABAergic system
ipsilateral to photochemically induced cortical infarcts in rats.
Neuroscience 1998 Dec;87(4):871-9
Hagemann
G, Redecker C, Neumann-Haefelin T, Freund HJ, Witte OW
Increased long-term potentiation in the surround of experimentally
induced focal cortical infarction.
Ann Neurol 1998 Aug;44(2):255-258
see
comment in Dobkin, B, Ann Neurol
Redecker
C, Hagemann G, Witte OW, Marret S, Evrard P, Gressens P
Long-term evolution of excitotoxic cortical dysgenesis induced in the
developing rat brain.
Brain Res Dev Brain Res 1998 Jul 1;109(1):109-113
Biermann
K, Schmitz F, Witte OW, Konczak J, Freund HJ, Schnitzler A
Interaction of finger representation in the human first somatosensory
cortex: a neuromagnetic study.
Neurosci Lett 1998 Jul 17;251(1):13-16
Salmelin
R, Schnitzler A, Schmitz F, Jancke L, Witte OW, Freund HJ
Functional organization of the auditory cortex is different in stutterers
and fluent speakers.
Neuroreport. 1998 Jul 13; 9(10): 2225-2229.
Buchkremer-Ratzmann
I, August M, Hagemann G, Witte OW
Epileptiform discharges to extracellular stimuli in rat neocortical
slices after photothrombotic infarction.
J Neurol Sci 1998 Apr 1;156(2):133-137
Hagemann
G, Bruehl C, Lutzenburg M, Witte OW
Brain hypometabolism in a model of chronic focal epilepsy in rat neocortex.
Epilepsia. 1998 Apr; 39(4): 339-346.
Volkmann
J, Seitz RJ, Muller-Gartner HW, Witte OW.
Extrarolandic origin of spike and myoclonus activity in epilepsia partialis
continua: A magnetoencephalographic and positron emission tomography study.
J Neuroimaging 1998 Apr;8(2):103-106
Schnitzler
A, Witte OW, Kunesch E, Freund HJ, Benecke R
Early-onset multisystem degeneration with central motor, autonomic
and optic nerve disturbances: unusual Riley-Day syndrome or new clinical
entity? Journal of Neurological Sciences 154, 1998, 205 - 208
Volkmann
J, Schnitzler A, Witte OW, Freund H
Handedness and asymmetry of hand representation in human motor cortex.
J Neurophysiol 1998 Apr 1;79(4):2149-2154
S.
Jander, M. Schroeter, D. D?Urso, C. Gillen, O.W. Witte, G. Stoll
Microglia/macrophages express CD8 antigen in ischemic lesions of the
rat brain.
Eur. J. Neurosci. 10, 1998, 680-688
Bidmon
HJ, Jancsik V, Schleicher A, Hagemann G, Witte OW, Woodhams P, Zilles
K
Structural alterations and changes in cytoskeletal proteins and proteoglycans
after focal cortical ischemia.
Neuroscience 1998 Jan;82(2):397-420
Reprint
(PDF)
H.-J.
Bidmon, K. Kato, A. Schleicher, O.W. Witte, K. Zilles
Transient increase of manganese-superoxide dismutase in remote brain
areas after focal photothrombotic cortical lesion.
Stroke. 1998 Jan; 29(1): 203-210.
Bidmon
HJ, Wu J, Buchkremer-Ratzmann I, Mayer B, Witte OW, Zilles K
Transient changes in the presence of NO-synthases and nitrothyrosine
immunoreactivity after focal cortical lesions.
Neuroscience 82, 1998, 377 - 395
Reprint
(PDF)
H.
Jokeit, R.J. Seitz, H.J. Markowitsch, O.W. Witte, A. Ebner
Prefrontal asymmetric interictal glucose hypometabolism and cognitive
impairment in patients with temporal lobe epilepsy.
Brain 120, 1997, 2283 - 2294
Holthoff
K, Witte OW, 1997
Recording of neuronal network properties with near-infrared dark-field
microscopy.
Biochimica Acta, 42, 3241 - 3246
Schlaug
G, Antke C, Holthausen H, Arnold S, Ebner A, Tuxhorn I, Jancke L, Luders
H, Witte OW, Seitz RJ
Ictal motor signs and interictal regional cerebral hypometabolism.
Neurology 1997 Aug;49(2):341-350
Witte
OW, Buchkremer-Ratzmann I, Schiene K, Neumann-Haefelin T, Hagemann
G, Kraemer M, Zilles K, Freund HJ, 1997.
Lesion-induced network plasticity in remote brain areas.
Trends in Neurosciences, 1997, 20, 348
Bidmon
HJ, Oermann E, Schleicher A, Kato K, Kinschert R, Buchkremer-Ratzmann I,
Witte
OW, Zilles K
Copper-zinc superoxide dismutase and isolectin B4 binding are markers
for associative and transhemispheric diaschisis.
Neuroscience Letters 1997, 228, 1- 4
Poppe
R, Karbach U, Gambaryan S, Wiesinger H, Lutzenburg M, Kraemer M, Witte
OW, Koepsell H, 1997
Expression of the Na+-D-glucose cotransporter SGLT1 in neurons
J Neurochem 69: 84-94 (1997)
Redecker
C, Bruehl C, Hagemann G, Binus O, Witte OW, 1997
Coupling of cortical and thalamic metabolism in experimentally induced
visual and somatosensory focal epilepsy
Epilepsy Res 27(2), 127-137 (1997)
Gass
P, Bruehl C, Herdegen T, Kiessling M, Witte OW, 1997.
Induction of FOS and JUN proteins during focal epilepsy: congruences
with and differences to [14C]deoxyglucose metabolism
Brain Res Mol Brain Res, 46 (1-2): 177-184 (Jun 1997)
Buchkremer-Ratzmann
I, Witte OW 1997
Pharmacological reduction of electrophysiological diaschisis after
photothrombotic ischemia in rat neocortex
Eur J Pharmacol 320, 103-109 (1997)